EXOC4 and Joubert syndrome: Although we did not focus on disease associations with membrane trafficking regulators, it is important to note that mutations in the membrane trafficking regulators are associated with ciliopathy: Arl13b (Joubert syndrome)97, Rab23 (Carpenter syndrome)98, and the exocyst subunits Exo84 (Joubert syndrome)99 and Sec8 (Meckel–Gruber syndrome)100.