Therefore, the aim of this survey was to evaluate and compare the correlation between the expressions of miR-340, LGR5, and FOXO1 genes in both ovarian cancer samples and ovarian cancer cell lines (cisplatin-sensitive cell line [A2780S] and cisplatin-resistant cell line [A2780CP]) before and after the cisplatin treatment, so as to find new therapeutic procedures that do not have a negative effect on the normal fertility of ovarian cancer patients. The gene discussed is LGR5; the disease is ovarian carcinoma.