SOD1 and type 2 diabetes mellitus: Moreover, the supplementation with ethanol extract of the sericin layer from the green cocoon shell of B. mori increased liver GPx and SOD in obese mice with type 2 diabetes, and the treatment also reduced the liver content of MDA and 8-hydroxy-2′-deoxyguanosine (8-OHdG), as markers of lipid and DNA oxidative damage (31).