At a tissue level, the Th2 differentiation marker CD294 is abundantly present in biopsies from EGPA patients (13), and a Th2-dominant transcriptomic profile (STAT3, STAT6, GATA3, IL10, and IL4) was also described in bronchoalveolar lavage (66). Here, IL10 is linked to eosinophilic granulomatosis with polyangiitis.