Upregulation of another member of the TOM1 family proteins, TOM1-L1, enhances v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2 gene (ERBB2)-induced invasion of breast cancer cells, in a process that involves TOLLIP (Chevalier et al., 2016). The gene discussed is ERBB2; the disease is breast cancer.