Unsurprisingly, increased expression levels of LAMP1 have been correlated with tumor grade, metastatic potential and poor prognosis in many cancers, including breast and colon carcinoma, high grade glioma, and metastatic melanoma (Saitoh et al., 1992; Agarwal et al., 2015; Alessandrini et al., 2017; Wang et al., 2017; Sarafian et al., 2018). The gene discussed is LAMP1; the disease is cancer.