LAMP2 and cancer: Another example of the consequences of deregulated lysosomal exocytosis is that redistribution of LAMP1 and LAMP2 at the PM of cancer cells promotes tumor invasion and metastasis via the interaction of their glycan exposed domains with galectins and selectins (Saitoh et al., 1992; Sawada et al., 1993; Dange et al., 2015; Sarafian et al., 2018).