ATF4 and neoplasm: In the tumor-bearing WFA 4 mg/kg group, we observed: (1) a significant increase in relative transcript levels of Ddit3 and Ern1 (p < 0.0001 for both comparisons) and (2) a decrease in relative transcript levels of Eif2ak3, Atf4, Ppp1r15a, Hspa5, Hsp90B1, and Tnfrsf10B (Eif2ak3: p = 0.0085; p < 0.001 for all other comparisons) compared to the tumor-bearing vehicle-treated group (Figure 4).