EIF2AK3 and neoplasm: In the tumor-bearing WFA 2 mg/kg group, we observed: (1) an upregulation of relative transcript levels of Ddit3 (p < 0.01), (2) a reduction in Eif2ak3, Atf4, Ppp1r15a, Hspa5, Hsp90B1, and Tnfrsf10B (p < 0.0001 for all comparisons), and (3) no significant difference in relative transcript levels of Ern1 (p = 0.9016) compared to the tumor-bearing vehicle-treated group (Figure 4).