While an increase in proliferating satellite cells has been evidenced in the settings of cancer-induced cachexia, it was simultaneously demonstrated that they are functionally inactivated (i.e., did not differentiate/fuse with muscle to repair injury) through a Pax7-dependent downregulation of MyoD, leading to a failure in muscle repair (He et al., 2013). This evidence concerns the gene MYOD1 and cancer.