To examine the effect of WFA and our xenograft model on the ALS, we measured relative mRNA levels of common autophagy markers: Sqstm1 [encoding the protein p62 (Sánchez-Martín and Komatsu, 2018)], Map1lc3b [encoding the protein LC3B (Kang et al., 2019)], and Becn1 [encoding the protein Beclin1 (Zheng et al., 2020)] (Figure 7A). This evidence concerns the gene SQSTM1 and amyotrophic lateral sclerosis.