Analysis revealed a mean cluster size of 18.41 ± 0.89 RyR2 channels in RAA from non-AF patients, and confirmed this did not differ in either of the AF patient groups (Figure 2D; paroxysmal AF: 18.95 ± 1.26 RyR2; persistent AF: 17.29 ± 1.08 RyR2). This evidence concerns the gene RYR2 and atrial fibrillation.