Alternatively, Kahn and coworkers showed in vitro that addition of AZD2014, another mTORC1/mTORC2 inhibitor, to culture media 1 h before irradiation enhanced the radiosensitivity of CD133+ and CD15+ glioblastoma stem-like cells (Kahn et al., 2014). This evidence concerns the gene PROM1 and glioblastoma.