The expression of the Bcl-2 gene in the context of the clinical-pathological characteristics of HNSCC has shown that a positive correlation exists between the overexpression of this gene in tumor cells and the tumor mitotic index, a higher index of atypical mitoses, and a micro focal pattern of the invasive margin of the tumor, thus promoting unfavorable histopathological characteristics (Sulkowska et al., 2003). Here, BCL2 is linked to neoplasm.