These results may indicate that in this neoplastic phenotype, the upregulation of Bcl-2 may be a major event for cell survival, versus CDKN1A. In addition, this cell line displayed the overexpression of the PI3KCA gene, which promotes cell growth, the evasion of apoptosis, and tumor invasion when overexpressed in neoplastic cells. The gene discussed is BCL2; the disease is neoplasm.