Accounts of the relationship between T cells phenotype and lactate within TB are limited; however, the levels of lactate within the TB granuloma reach mM concentrations comparable to that of tumors, and LDHA expression colocalizes with CD3+ T cells in mouse lungs 30 days post infection (Somashekar et al., 2011; Shi et al., 2015). Here, LDHA is linked to tuberculosis.