The intensity of CXCR2 MFI was independent of the bone marrow source, but it was dependent on plasma source: cells incubated with CDI-plasma collected from RR mice had higher CXCR2, compared to those incubated with plasma from C. difficile-infected QQ mice (Figures 3E, F). Here, CXCR2 is linked to clostridium difficile infection.