While CXCR2 is present on multiple different cell types, the CDI plasma-induced increase was seen only on neutrophils (i.e. CD11b+Ly6G+ cells), whereas non-neutrophil bone marrow cells (i.e. CD11b+Ly6G- cells) did not exhibit CXCR2 up-regulation (Supplementary Figure 2A). The gene discussed is ITGAM; the disease is clostridium difficile infection.