KLK3 and tuberculosis: There were 290 patients performed systematic combined with targeted biopsy (TB+SB), and 56 of them were excluded because of prior prostate biopsy or surgery (n = 33), MRI not performed at our institution (n = 5); missing PSA or PSA >100 ng/ml (n = 10), and duration between biopsy and MRI longer than 6 months (n = 8).