The results of in vivo and in vitro experiments have shown that a novel oncogenic lncRNA, RP11-757G1.5, which is overexpressed in CRC tissues, regulates the expression of YAP1 by sponging miR-139-5p and inhibiting its activity, thereby promoting the metastasis and invasion in CRC (105). Here, YAP1 is linked to colorectal carcinoma.