An immunoconjugate called HLEAFab-MCC was generated by conjugating mitomycin with human Ab Fab fragment specific for LMP1 extracellular domains. This immunoconjugate killed LMP1 positive NPC cells in culture and also inhibited the growth of NPC xenografts in nude mice. This evidence concerns the gene PDLIM7 and nasopharyngeal carcinoma.