In addition, LMP1-containing exosomes released by NPC cells induces anergy in activated T cells, while FGF-2, EGFR, HIF-a, and Gal-9 in LMP1-containing exosomes promote proliferation and metastasis as well as immune exhaustion in recipient cells (33, 78, 105). The gene discussed is LGALS9; the disease is nasopharyngeal carcinoma.