CPZ and glioblastoma: We evaluated the ability of CPZ to affect several GBM cellular parameters in vitro, using a large number of human GBM cell lines, i.e. the anchorage-dependent cell lines T98G, U-87 MG, and U-251 MG as well as three patient-derived, anchorage-independent neurospheres characterized for their ability to display a glioma stem-like cell behavior (19).