In addition to the early reports of BCL2 interacting protein 3 like (BNIP3L/NIX) acting as a mitophagy receptor in red cells (35), other mitophagy receptors, including FUN14 domain containing 1 (FUNDC1) (36), BCL2 interacting protein 3 (BNIP3) (37), nipsnap homolog 1 (NIPSNAP1) (38), nipsnap homolog 2 (NIPSNAP2) (38), prohibitin 2 (PHB2) (39), BCL2 like 13 (BCL2L13) (40) and FKBP prolyl isomerase 8 (FKBP8) (41), have also been identified in cancer and non-cancer cells (Figure 1B). The gene discussed is BNIP3; the disease is cancer.