Studies have shown that After TACE treatment, the tumor Ki67 level and percentage of necrotic cells in tumor tissues were significantly higher than before treatment, and the level of Ki67 was positively correlated with the percentage of necrosis (22, 23), which is in agreement with our conclusions; however, we showed that some patients exist with high expression of Ki67 and non-poorly differentiated tumors who have a better prognosis after adjuvant TACE treatment. This evidence concerns the gene MKI67 and neoplasm.