FOXP2 and breast cancer: To further investigate the functions of FOXP2 on the EMT of breast cancer cells in vivo, we generated a metastasis model in nude mice via the tail vein injection of the FOXP2-specific shRNA#2 lentivirus-infected MCF-7 cells (shFOXP2) or control lentivirus-infected MCF-7 cells (shCon) (n=12 for each group).