Interestingly, the patients with invasive cervical cancer showed higher frequency promoter methylation for individual genes: RARB, 94.0%; CADM1, 76.5%; PAX1, 96.5%, and DAPK1, 64.1%, compared to the control samples (RARB, 50.5%; CADM1, 32.6%; PAX1, 81.9%, and DAPK1, 25.0%), Table 2. The gene discussed is CADM1; the disease is cervical cancer.