PGP and neoplasm: loaded DOX and P‐gp siRNA on BPNs with aptamers (Apts), which bind specific target molecules.[74] Combining the PTT of BPNs, chemotherapy with DOX, and GT with P‐gp siRNA, as well as the tumor targeting ability of Apts, this nanoplatform exhibited remarkable multimodal therapeutic effects by restricting cell proliferation in solid tumors in vitro and in vivo.