APOE and chronic kidney disease: We also found that the expressions of α‐SMA and other VSMC markers, including myosin heavy chain 11 (MYH11), calponin 1 (CNN1), transgelin (TAGLN) were significantly reduced in the aortas and fibrous cap VSMCs of CKD/ApoE−/− mice comparing to Sham/ApoE−/− mice (Figure 2D,E; Figure S4A, Supporting Information).