PROM1 and hepatocellular carcinoma: Consistently, the addition of rTHBS2 to both HCC cells and patient‐derived HCC organoids grown in 3D matrix gel also profoundly reduced the ability of the cells to migrate (Figure S4A, Supporting Information), invade (Figure S4B, Supporting Information), self‐renew (Figure S4C, Supporting Information), and resist 5‐FU treatment (Figure S4D, Supporting Information), and led to a decrease in CD133 expression (Figure S4E, Supporting Information).