RASSF1 and neoplasm: Based on the location of the RA domain, the RASSF family is divided into two groups: C‐terminal RASSFs (RASSF1‐6) and N‐terminal RASSFs (RASSF7‐10).[35] Previous studies have shown that C‐RASSFs are downregulated in human cancers and this downregulation is often correlated with tumor progression.[18, 36] Compared to C‐RASSFs, N‐RASSFs have rarely been examined.