The tumor was positive for CD30, CD45, and PAX5, but negative for CD10, CD20, CD3, CD15, BCL-2, Epstein-Barr virus-encoded small RNA (EBER), and ALK, and the patient showed an excellent response to cyclophosphamide, doxorubicin hydrochloride (hydroxydaunorubicin), vincristine sulfate (oncovin), and prednisone (CHOP) regimen chemotherapy and achieved complete remission [6]. The gene discussed is MME; the disease is neoplasm.