The dysregulation of LYVE1 closely correlated with many types of tumor, like gastric cancer (Ozmen et al., 2011), colorectal cancer (Gao et al., 2006), breast cancer (Kato et al., 2005), lung cancer (Koukourakis et al., 2005) and liver cancer (Mouta Carreira et al., 2001). The gene discussed is LYVE1; the disease is lung cancer.