Also, Li et al.9screened miRNAs sponged by upregulated circPRRC2A, and they found that miR-514a-5p and miR-6776-5p share common binding sites with circPRRC2A and TRPM3 (a protein that is highly related to malignant behavior of renal cell carcinoma [RCC]), indicating that circPRRC2A could regulate the DHX9-circPRRC2A-miR-514a-5p/miR-6776-5p-TRPM3 pathway in RCC through sponging miR-514a-5p, miR-6776-5p, miR-514a-5p, and miR-6776-5p, and they determined the regulatory role of the DHX9-circPRRC2A-miR-514a-5p/miR-6776-5p-TRPM3 pathway in RCC. This evidence concerns the gene TRPM3 and hereditary clear cell renal cell carcinoma.