found that the upregulation of circSEPT9 (circRNA septin 9) was mediated by E2F1, and EIF4A3 (eukaryotic translation initiation factor 4A3).circSEPT9 subsequently sponged miR-637 and activated the LIF/Stat3 signaling pathway to promote the progression of triple-negative breast cancer (TNBC). Here, EIF4A3 is linked to triple-negative breast carcinoma.