CARMIL2 and fungal infectious disease: Mutations in CARMIL2 (Capping Protein Regulator And Myosin 1 Linker 2), also known as RLTPR (RGD, leucine-rich repeat, tropomodulin and proline-rich-containing protein) affect the CD28-responsive pathway in T cells and the BCR-responsive pathway in B cells and have been reported in patients with cutaneous and pulmonary allergy, as well as a variety of bacterial and fungal infectious diseases, including invasive tuberculosis and mucocutaneous candidiasis.141