Except for these inflammatory cytokines, the levels of some serum biochemical parameters, such as C-reactive protein (CRP), ferritin, LDH, aminotransferase (AST), alanine aminotransferase (ALT), blood urea nitrogen (BUN), and creatinine, are elevated in patients with CRS and ICANS; however, these sometimes fail to predict the severity of the two toxicities (76–78). This evidence concerns the gene GPT and congenital rubella syndrome.