IL1B and congenital rubella syndrome: presented a feasible predictive model combined with IFN-γ and IL1β, so as to differentiate between the analogous clinical entities of sepsis and CRS, the results displayed that an obviously elevated IFN-γ (>83 pg/ml) or a mildly elevated IFN-γ (<83 pg/ml) in combination with a low IL1β(<8 pg/ml) heralded the presence of CRS.