However, in the context of CD4+T (Figures 3C, D, Supplementary Figures 3F, G) or NK cells (Figures 3E, F, Supplementary Figures 3H, I) deletion, the LLC or B16F10 tumor-bearing mice processed by IL-10 or Ad-hTERT presented shrinking tumor and improved survival compared with PBS control group. The gene discussed is CD4; the disease is neoplasm.