Accordingly, the number of hepatic NK cells, their expression of NKG2D and the levels of the corresponding ligand of NKG2D, Major histocompatibility complex class I chain-related (MIC) A/B transcripts, are all increased in NASH patients with morbid obesity, being higher than those in patients with a nonalcoholic fatty liver (68). This evidence concerns the gene KLRK1 and metabolic dysfunction-associated steatohepatitis.