Furthermore, gonadal autoimmunity markers prevail in APS1 and APS2 APOI women, while the percentage of sera positive for StC-Abs and CYPscc-Abs/CYP17-Abs falls in women with non-AAD-associated APOI, and in patients with other autoimmune diseases (299–302). Here, CYP17A1 is linked to Autoimmune polyendocrinopathy type 1.