ATP5IF1 and gastric cancer: To verify that ATPIF1 mediated the downstream effects of miR-148b5p in GC cells, we first downregulated ATPIF1 level in MKN45 cells using siRNA (P < 0.001, Figures 4A, B), which results in the inhibition of GC cell proliferation, 3D tumor growth, and migratory activity (P < 0.001, Figures 4C–E).