As compared with the control tumors, the miR-148b-5p-overexpressing GC tissues indicated the significant reductions in myeloid-derived suppressor cells (MDSCs), macrophages, and T regulatory cells in the miR-148b-5p-overexpressing GC tissues whereas the NK cells, CD4+ T cells, and CD8+ T cells were significantly increased (Figures 5Gi, ii), suggesting the effects of miR-148b-5p on the composition of various immune cells in the tumor microenvironment. The gene discussed is CD8A; the disease is neoplasm.