As shown in Figure 1D, after 24 h of sunitinib treatment (20 and 15 μM for SaOS-2 and SYO-1, respectively), the PD-L1 expression significantly increased in both sarcoma cell lines (fold change 3.1 ± 0.1% for SaOS-2 and 4.6 ± 0.1% for SYO-1, respectively) compared to untreated cells (p < 0.001 for both cell lines). Here, CD274 is linked to sarcoma.