Our literature survey confirmed that five out of these 21 bacterial proteins have homology to four known human auto-antigens (i.e., beta-glucuronidase precursor1-4/X1-X6, FAP, Hsp40, and Thioredoxin) which play important pathological roles in RA (Table 1). The gene discussed is DNAJB1; the disease is rheumatoid arthritis.