In a study with BC cells lines, evaluating the interplay between FFARs and propionate and butyrate, it was observed that FFAR2 could increase the levels of E-cadherin in mesenchymal-like cells but not on epithelial-like cells, which suggests this receptor might convert cells to an epithelial phenotype, impacting epithelial-mesenchymal transition (EMT) and potentially decreasing risk of metastases (Thirunavukkarasan et al., 2017). This evidence concerns the gene CDH1 and breast cancer.