In addition to genes involved in inflammation, extracellular matrix, cytokine and PI-3K signaling, and focal adhesion, 35 splicing factors were altered in the lobular inflammation group, including ESRP1, RBM4/20/24, SF3B5, HNRNPU, CELF3/4/5, ELAVL2/4, NOVA1/2, and RBFOX1/3, and 20 were altered in the advanced fibrosis group including CELF3/4/5, ELAVL2/4, RBM20/24, NOVA1/2, and RBFOX1/3. The gene discussed is CELF3; the disease is fibrosis.