In addition, the correlation analysis was conducted of mean CSAs in median and ulnar nerves and of Neuropathy Impairment Score (NIS) that included one item for reflection of muscle weakness, modified polyneuropathy disability (m-PND), Norfolk Quality of life-diabetic neuropathy score (Norfolk QOL-DN), the course of sensory motor peripheral neuropathy (SMPN) and electrophysiological data in TTR-FAP patients. This evidence concerns the gene TTR and neuropathy.