H19 and acute kidney injury: In the present study, LncRNA H19 was observed to be upregulated in hypoxia-induced HK-2 cellular model and knockdown LncRNA H19 promotes cell proliferation, inhibits apoptosis, and modulates inflammatory cytokine expressions in HK-2 cells under H/R treatment (Figures 1, 2), indicating that LncRNA H19 plays regulatory roles in AKI progression.