VANGL2 and rapidly progressive glomerulonephritis: The NTN model mirrors human rapidly progressive glomerulonephritis (RPGN) (Pippin et al., 2009), and recently, transcripts for VANGL1, VANGL2, CELSR2, DVL2, DVL3, PK1, and PK2 were found to be significantly upregulated in two independents cohorts of RPGN biopsies compared to living kidney donor controls (Papakrivopoulou et al., 2018).