SERPINA12 and obesity due to melanocortin 4 receptor deficiency: On the other hand, vaspin is a member of the serine protease inhibitor family (Hida et al., 2005; Nakatsuka et al., 2012) and is highly expressed by VAT in obesity conditions as well as subcutaneous adipose tissue (Shaker and Sadik, 2013) and in low quantities by skeletal muscle and liver (Körner et al., 2011; Goktas et al., 2013).