HIF1A and T-cell non-Hodgkin lymphoma: The findings of the present investigation shed new light regarding molecular mechanisms of the cytotoxic action of MJ against T cell lymphoma in conjunction with inhibited metabolism, altered pH homeostasis, increased ROS generation, hampered mitochondrial functions, and modulated expression of cell survival, metabolism, chemoresistance regulating molecules along with direct docking ability of MJ to the prominent binding sites of critical metabolism and cell survival regulatory molecules HIF-1α, HK 2, and Hsp70 (Figure 6).