However, the clinical seriousness of COVID-19 could be associated to the excessive production of pro-inflammatory cytokines, known as ‘cytokine storm’ (Fajgenbaum and June, 2020; Hussman, 2020), or to the excessive production of bradykinin peptides, known as ‘bradykin storm’ (Garvin et al., 2020). This evidence concerns the gene KNG1 and COVID-19.