ANXA5 and obstructive sleep apnea syndrome: Therefore, in this study, we performed both single- and dual-labeling of multiple types of circulating MVs, such as annexin V+MVs, EMVs, PMVs, and LMVs, in blood samples taken from elderly patients with OSA, and analyzed assessed factors that affected MV concentrations, such as the OSA severity, age, obesity, and the presence of comorbidities.