EZH2 and cancer: A CAM model is relevant in testing investigational medicine designed to interfere with EZH2 molecular pathways in cancer.28,61 EZH2 inhibits genes accountable for suppressing tumorigenesis, and inhibiting EZH2 activity may reduce tumor growth.62 This study shows that EZH2 expression in U87 and PBT24 control tumors were similar.