Interestingly, S. cerevisiae is a beneficial fungus that has capacity to ameliorate gastroenteritis [3, 138], mitigate adherent-invasive Escherichia coli (AIEC)-induced colitis in CEACAM6 (carcinoembryonic antigen-related cell adhesion molecule 6) -expressing mice [139], and relieve abdominal pain in irritable bowel syndrome (IBS) in human subjects [140]. Here, CEACAM6 is linked to irritable bowel syndrome.