Recently, Hofman et al. [20] demonstrated superior diagnostic accuracy of 68Ga-PSMA-11 PET/CT in primary staging of men with high-risk PCa in a randomized study setting, showing significantly higher sensitivity (0.85 vs 0.38) and better specificity (0.98 vs 0.91) compared to conventional imaging. The gene discussed is FOLH1; the disease is posterior cortical atrophy.