In the univariate Cox analysis, age, grade, tumor stage, T classification, M classification, and TACC3 expression were all independent risk factors for OS (p = 2.29e-06, 9.48e-15, 4.67e-20, 1.50e-15, 7.45e-19 and 2.99e-11, respectively, Table 2). The gene discussed is TACC3; the disease is neoplasm.