ZEB1 and cancer: For example, by using Cancer Cell Line Encyclopedia (CCLE) data, the resistance role of zinc finger E-box binding homeobox 1 (ZEB1) can be directly reflected by its mRNA level correlated to the response to the drug erlotinib, but there is no obvious correlation in the case of Fos proto-oncogene (FOS) (Figure S1A and B), though both TRs are known biomarkers of erlotinib [15], [16].