Subsequent multivariate logistic analysis revealed that ESR > 44 mm/h (HR, 1.97; 95% CI, 1.03–3.89; p = .04), CDCS ≥ 1 (HR, 2.31; 95% CI, 1.23–4.35; p = .009), age > 48 years (HR, 2.27; 95% CI, 1.24–4.19; p = .008), LDH > 291 U/L (HR, 3.08; 95% CI, 1.7–5.61; p < .001), and CRP > 48.3 mg/L (HR, 4.1; 95% CI, 2.23–7.62; p < .001) were critical risk factors closely related to the progression of COVID‐19 (Table 2). Here, CRP is linked to COVID-19.